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" Global and regional aspects of the solar and cosmophysical factor influence on the atmosphere, climate and environment ". E.A. Kasatkina (Institute of North Industrial Ecology Problems, Kola Science Center RAS, Apatity, Murmansk region) Abstract:  The report devoted to the problem of solar activity and other cosmophysical factor (cosmic rays, cosmic dust, comet material) influence on human environment (climate, ozone layer, atmospheric parameters and biosphere including human being). In the work the section connected to ecological aspects of small body encounter with the Earth is as well included. In general this work represents the results of author’s long-term (more than 15 years) study on the influence of different heliogeophysical agents on human environment. In the report some new facts and patterns of cosmophysical factor action on the atmosphere, ozone layer and climate of the Earth stated. Below several more cited results obtained are given: 1. A physical model permitted us to calculate the formation of additional aerosol amount during solar proton events of Ground Level Event (GLE) type on the basis of ionization processes, ion nucleation and heterogeneous chemistry. The model as well adequately describes the formation of ozone mini-holes (considerable total ozone depletions) during GLE events. As far as the GLEs are the analog of galactic cosmic rays this model is applied to climatology in context of estimation of GCR variation influence on cloudiness of the Earth. 2. The estimate on paleoclimatic data the action of solar activity and other external factors on the climate of Northern Russia. For this purpose we had to create the unique bank of dendrochronological series on most long (up to date) living trees for the Kola Peninsula. In particular the bank includes several long tree-ring chronologies: 677-year juniper (Juniperus sibirica) tree-ring chronology, the longest 561-year and 448-year series of pine (Pinus sylvestris) for Kola Peninsula and Khibiny mountains respectively. 3. The detection (for the first time) on ground based measurements of acoustic-gravity signal from Vitim bolide explosion on 24.09.2002 at the distance of 4000 km from the source in a frequency band 0.0001 – 1 Hz, and determination of the signal velocity and direction to the source location. This result demonstrates that even under local impacts the signal spreads at very large distance. 4. For the first time it was discovered (on dendrochronological data) the anomalous tree growth after Tunguska bolide explosion on 30 June 1908 fixed on a great (more than 1500 km) distance from the source at an area (60-75 N, 80-110 E) having got space equaled to 2.5 million sq. km. Earlier such ecological consequence after Tunguska explosion was restricted by area equaled to 2000 sq. km. 5. At the first time it was revealed the feature of combined influence of both heliogeophysical and socioeconomic factor influence on mortality level caused by cardiovascular diseases and suicides in auroral zone (Murmansk region) for the period 1948-2007 years.